Experts release early Bills vs. Rams NFL Week 5 prediction & odds

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New England Patriots wide receiver Romeo Doubs (87) celebrates after catching a pass for a touchdown.

The Buffalo Bills travel to face the Los Angeles Rams on Monday, October 12, 2026, with kickoff set for 8:15 PM EDT at SoFi Stadium. Dimers’ machine-learning models project a narrow 28-25 Rams win, and Polymarket has Los Angeles as a slight favorite, pricing the Rams at 58¢ to win compared to 46¢ for Buffalo.



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